BRPF1 bromodomain inhibitor GS6853

Name	GSK6853
Synonyms	GSK6853 CS-2243 GSK-6853 GSK 6853 FQWDVNSBYDXPIO-CQSZACIVSA-N BRPF1 bromodomain inhibitor GS6853 N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy-
CAS	1910124-24-1

Molecular Formula	C22H27N5O3
Molar Mass	409.48
Density	1.247±0.06 g/cm3(Predicted)
Boling Point	545.9±50.0 °C(Predicted)
Solubility	DMSO: ≥ 29 mg/mL
Appearance	solid
Color	White
pKa	13.03±0.20(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
In vivo study	The ip route of administration would be suitable for dosing GSK6853 in potential PK/PD models.

Last Update：2024-01-02 23:10:35

Use	GSK6853 can be used in biological studies for preparing bromodomain and PHD finger-containing protein inhibitors.
biological activity	GSK6853 is a strong and selective inhibitor of RPF1 acetyllysine (pKd = 9.5), its selectivity is 1600 times that of other acetyl lysine.
in vivo study	The ip route of administration would be recommended for dozing GSK6853 in potential PK/PD models.

Last Update：2024-04-10 22:29:15

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CAS: 1910124-24-1
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Product Name: GSK6853 Visit Supplier Webpage Request for quotation
CAS: 1910124-24-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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BRPF1 bromodomain inhibitor GS6853

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